autosomal dominant disorder

Học thuật
Thân thiện
autosomal dominant disorder

A genetic counselor explains autosomal dominant disorder using a family pedigree chart.

Definition

Noun: A genetic condition or disease that is caused by a mutation in a gene located on an autosome (a non-sex chromosome) and that follows a dominant pattern of inheritance. This means only one copy of the mutated gene, inherited from one parent, is sufficient to cause the disorder.

Usage

This is a specialized medical and genetic term. It is used to classify and describe the inheritance pattern of specific genetic diseases. - It functions as a countable noun. - It is often used in scientific, clinical, and educational contexts.

Examples
  • Noun:
    • Huntington's disease is a well-known autosomal dominant disorder.
    • The genetic counselor explained that the condition in their family was an autosomal dominant disorder.
    • Diagnosing an autosomal dominant disorder often involves tracing the family medical history.
Advanced Usage
  • The term is frequently used in contrast with , where two copies of the mutated gene are needed.
  • In clinical reports: "The patient's presentation and family history are consistent with an autosomal dominant disorder."
Variants and Related Words
  • Autosomal dominant: The adjective form describing the inheritance pattern itself.
    • Marfan syndrome is an autosomal dominant condition.
  • AD disorder: A common abbreviation used in medical genetics.
  • Autosomal recessive disorder: (Antonymic concept) A disorder requiring two copies of a mutated gene.
Synonyms
  • Dominant genetic disorder (a broader term that could also refer to disorders on sex chromosomes).
  • Monogenic disorder with autosomal dominant inheritance (a more precise, descriptive synonym).
Notes on Meaning

This term specifically combines three key concepts: 1. Autosomal: The genetic mutation is not on the X or Y chromosome. 2. Dominant: A single mutated copy of the gene is enough to produce the disease. 3. Disorder: It refers to a disease, syndrome, or medical condition.

There are no specific idioms or phrasal verbs associated with this technical compound noun.

autosomal dominant disorder

A genetic counselor explains autosomal dominant disorder using a family pedigree chart.

Noun
  1. a disease caused by a dominant mutant gene on an autosome

Từ đồng nghĩa